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Biodistribution of 99Mo in rats BABT
Souza,Raphael Sancho Sisley de; Ribeiro,Bianca da Silva; Dantas,Ana Letícia Almeida; Bernardo Filho,Mario; Dantas,Bernardo Maranhão.
The modification of 99Mo standard metabolism in the presence of MDP would alter the dosimetry of this radionuclide in nuclear medicine patients. Therefore, the objective of this work is to evaluate the influence of MDP in the biodistribution of 99Mo. Wistar rats were divided in two groups of six animals, being inoculated respectively 99Molibdate and 99Mo+MDP via plex ocular. The biodistribution study was carried out after 10 and 120 minutes respectively. The organs were counted with a NaI(Tl) detector. The uptake values did not present significant differences among the groups. An in vitro study through planar chromatography was carried out to determine the affinity between molybdenum and MDP. The results show that 99Mo has low affinity both to propanone...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Wistar; Molybdenum; Nuclear Medicine.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700029
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Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc BABT
Dantas,Bernardo Maranhão; Dantas,Ana Letícia Almeida; Marques,Fábio Luiz Navarro; Bertelli,Luiz; Stabin,Michael G..
99mTc is a radionuclide widely used for imaging diagnosis in nuclear medicine. In Brazil it is obtained by elution from 99Mo-99mTc generators supplied by the Nuclear Energy Research Institute (IPEN). The elution is carried out in radiopharmacy laboratories located in hospitals and clinics. Depending of the quality of the generator and conditions of use during the elution process, 99Mo can be extracted from the column of the generator, becoming a radionuclidic impurity of the eluate used for the obtention of the radiopharmaceutical to be administered to the patient. 99Mo emits high-energy photons and beta particles and its presence degrades the quality of the image and unnecessarily increases the radiation dose delivered to the patient. An in-vivo...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Molybdenum 99; Technetium 99m; Nuclear medicine; Internal dosimetry; In vivo measurements; Whole body counter.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700032
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Internal exposure in nuclear medicine: application of IAEA criteria to determine the need for internal monitoring BABT
Dantas,Bernardo Maranhão; Lucena,Eder Augusto de; Dantas,Ana Letícia Almeida.
The manipulation of unsealed sources in nuclear medicine poses significant risks of internal exposure to the staff. According to the International Atomic Energy Agency, the radiological protection program should include an evaluation of such risks and an individual monitoring plan, assuring acceptable radiological safety conditions in the workplace. The IAEA Safety Guide RS-G-1.2 recommends that occupational monitoring should be implemented whenever it is likely that committed effective doses from annual intakes of radionuclides would exceed 1 mSv. It also suggests a mathematical criterion to determine the need to implement internal monitoring. This paper presents a simulation of the IAEA criteria applied to commonly used radionuclides in nuclear medicine,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nuclear medicine; Internal monitoring; Radiation protection.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700017
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